Journal of Zhejiang Agricultural Sciences ›› 2022, Vol. 63 ›› Issue (10): 2415-2418.DOI: 10.16178/j.issn.0528-9017.20220005
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Received:2022-06-01
Online:2022-10-11
Published:2022-10-26
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URL: http://www.zjnykx.cn/EN/10.16178/j.issn.0528-9017.20220005
| 组别 | 浓度/ (μL·mL-1) | 死亡数 | 死亡率/ % | 毒性情况 |
|---|---|---|---|---|
| 正常对照组 | — | 0 | 0 | — |
| 模型对照组 | — | 0 | 0 | — |
| 葡萄阿萨伊 | 3.90 | 0 | 0 | 无明显毒性 |
| 果混合饮料 | 7.80 | 0 | 0 | 无明显毒性 |
| 15.60 | 0 | 0 | 无明显毒性 | |
| 31.25 | 0 | 0 | 2尾心包水肿,3尾身体弯曲 | |
| 62.50 | 30 | 100 | — | |
| 125.00 | 30 | 100 | — | |
| 250.00 | 30 | 100 | — | |
| 500.00 | 30 | 100 | — | |
| 1 000.00 | 30 | 100 | — |
| 组别 | 浓度/ (μL·mL-1) | 死亡数 | 死亡率/ % | 毒性情况 |
|---|---|---|---|---|
| 正常对照组 | — | 0 | 0 | — |
| 模型对照组 | — | 0 | 0 | — |
| 葡萄阿萨伊 | 3.90 | 0 | 0 | 无明显毒性 |
| 果混合饮料 | 7.80 | 0 | 0 | 无明显毒性 |
| 15.60 | 0 | 0 | 无明显毒性 | |
| 31.25 | 0 | 0 | 2尾心包水肿,3尾身体弯曲 | |
| 62.50 | 30 | 100 | — | |
| 125.00 | 30 | 100 | — | |
| 250.00 | 30 | 100 | — | |
| 500.00 | 30 | 100 | — | |
| 1 000.00 | 30 | 100 | — |
| 组别 | 浓度 | 中性粒 细胞个数 | 炎症 消退/% |
|---|---|---|---|
| 正常对照组 | — | 3 | — |
| 模型对照组 | — | 16 | — |
| 吲哚美辛组 | 80 μmol·L-1 | 10*** | 38*** |
| 葡萄阿萨伊果混合饮料组 | 15.6 μL·mL-1 | 9*** | 44*** |
| 组别 | 浓度 | 中性粒 细胞个数 | 炎症 消退/% |
|---|---|---|---|
| 正常对照组 | — | 3 | — |
| 模型对照组 | — | 16 | — |
| 吲哚美辛组 | 80 μmol·L-1 | 10*** | 38*** |
| 葡萄阿萨伊果混合饮料组 | 15.6 μL·mL-1 | 9*** | 44*** |
| [1] | 杨勇, 杨俊祥, 宫霞. 葡萄及葡萄属植物中的天然活性物质研究与利用现状[J]. 酿酒科技, 2011 (6): 75-79. |
| [2] | 楚海云, 张文高. 巴西莓(阿萨伊果)国内研究进展及其食疗药膳应用探索[C]// 2016年中国药膳学术研讨会论文集. 2016:125-127. |
| [3] |
LEE J Y, KIM N, CHOI Y J, et al. Anti-inflammatory and anti-tumorigenic effects of açai berry in Helicobacter felis-infected mice[J]. Journal of Cancer Prevention, 2016, 21(1): 48-54.
DOI URL |
| [4] |
KIM H S, KO K S. Antioxidant and anti-inflammatory effects of ginseng berry ethanol extracts as a cosmetic ingredient[J]. Asian Journal of Beauty and Cosmetology, 2020, 18(3): 389-397.
DOI URL |
| [5] |
PALA D, BARBOSA P O, SILVA C T, et al. Açai (Euterpe oleracea Mart.) dietary intake affects plasma lipids, apolipoproteins, cholesteryl ester transfer to high-density lipoprotein and redox metabolism: a prospective study in women[J]. Clinical Nutrition, 2018, 37(2): 618-623.
DOI URL |
| [6] | 郭佳, 任国宝, 刘文龙, 等. 巴西莓的功能概述[J]. 农产品加工, 2021(18): 85-89, 92. |
| [7] | 王红敏, 单淇, 郝春华, 等. 葡萄籽中原花青素类成分的制备及其止泻活性评价[J]. 药物评价研究, 2019, 42(10): 1955-1961. |
| [8] | 刘玟君, 李金洲, 陈子隽, 等. 原花青素的研究进展[J]. 湖北农业科学, 2021, 60(14): 5-9. |
| [9] |
KANG J, LI Z M, WU T, et al. Anti-oxidant capacities of flavonoid compounds isolated from acai pulp (Euterpe oleracea Mart.)[J]. Food Chemistry, 2010, 122(3): 610-617.
DOI URL |
| [10] | NOWAK D, GOŚLIŃSKI M, PRZYGOŃSKI K,et al. The antioxidant properties of exotic fruit juices from acai, maqui berry and noni berries[J]. European Food Research and Technology, 2018, 244(11): 1897-1905. |
| [11] |
DE FREITAS CARVALHO M M, LAGE N N, et al.DE SOUZA PAULINO A H, Effects of açai on oxidative stress, ER stress, and inflammation-related parameters in mice with high fat diet-fed induced NAFLD[J]. Scientific Reports, 2019, 9: 8107.
DOI PMID |
| [12] |
ZANANDREA R, BONAN C D, CAMPOS M M. Zebrafish as a model for inflammation and drug discovery[J]. Drug Discovery Today, 2020, 25(12): 2201-2211.
DOI PMID |
| [13] |
YANG L L, ZHOU X J, HUANG W J, et al. Protective effect of phillyrin on lethal LPS-induced neutrophil inflammation in zebrafish[J]. Cellular Physiology and Biochemistry, 2017, 43(5): 2074-2087.
DOI PMID |
| [14] | 倪立颖, 邹娅雪, 付晓婷, 等. 利用LPS诱导胚胎期斑马鱼炎症模型研究羊栖菜多酚抗炎机制[J]. 食品工业科技, 2019, 40(21): 279-285. |
| [15] | 张子琪. 虾青素干预对脂多糖诱导炎症反应小鼠的保护作用[D]. 长春: 吉林农业大学, 2019. |
| [16] | ARULSELVAN P, FARD M T, TAN W S, et al. Role of antioxidants and natural products in inflammation[J]. Oxidative Medicine and Cellular Longevity, 2016, 2016: 5276130. |
| [17] |
BÄCK M, YURDAGUL A Jr, TABAS I, et al. Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities[J]. Nature Reviews Cardiology, 2019, 16(7): 389-406.
DOI PMID |
| [18] |
MAN S M, KARKI R, KANNEGANTI T D. Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases[J]. Immunological Reviews, 2017, 277(1): 61-75.
DOI PMID |
| [19] | JASPER A E, MCIVER W J, SAPEY E, et al. Understanding the role of neutrophils in chronic inflammatory airway disease[J]. F1000Research, 2019, 8: F1000FacultyRev-F1000Faculty557. |
| [20] |
MEDZHITOV R. Origin and physiological roles of inflammation[J]. Nature, 2008, 454(7203): 428-435.
DOI URL |
| [21] |
ZOU Y, ZHANG Y, HAN L W, et al. Oxidative stress-mediated developmental toxicity induced by isoniazide in zebrafish embryos and larvae[J]. Journal of Applied Toxicology, 2017, 37(7): 842-852.
DOI PMID |
| [22] | 孙炳伟. 脓毒症时中性粒细胞的生物学行为[J]. 医学研究生学报, 2019, 32(1): 31-36. |
| [23] | 张建军, 陈绍红, 朱映黎, 等. 南美草药阿萨伊的中药性能与功用探析[J]. 中国中药杂志, 2015, 40(11): 2258-2264. |
| [24] | 潘瑶, 郑时莲, 邹兴平, 等. 葡萄、芒果、草莓乙醇提取物抗氧化活性组分分析及其抗氧化相互作用[J]. 食品科学, 2017, 38(4): 133-140. |
| [25] | 陈雅纯, 韩玮钰, 张拓, 等. 葡萄多酚类物质研究进展[J]. 农产品加工, 2019(19): 83-86. |
| [26] | 仇菊, 朱宏, 卢林纲. 葡萄籽多酚对糖尿病大鼠的降血糖作用及其机制[J]. 食品科学, 2018, 39(1): 226-231. |
| [27] | 冯艺飞, 王笑颖. 黄酮类化合物的研究概况[J]. 江西化工, 2021, 37(4): 102-104. |
| [28] | KIM K J, KIM Y, JIN S G, et al. Acai berry extract as a regulator of intestinal inflammation pathways in a Caco-2 and RAW 264.7 co-culture model[J]. Journal of Food Biochemistry, 2021, 45(8): e13848. |
| [29] |
KANG J, XIE C H, LI Z M, et al. Flavonoids from acai (Euterpe oleracea Mart.) pulp and their antioxidant and anti-inflammatory activities[J]. Food Chemistry, 2011, 128(1): 152-157.
DOI URL |
| [30] |
CAREY A, MILLER M G, FISHER D, et al. Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells[J]. Nutritional Neuroscience, 2017, 20: 238-245.
DOI URL |
| [31] | BRUGMAN S. The zebrafish as a model to study intestinal inflammation[J]. Developmental & Comparative Immunology, 2016, 64: 82-92. |
| [32] |
LAM S H, CHUA H L, GONG Z, et al. Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study[J]. Developmental and Comparative Immunology, 2004, 28(1): 9-28.
DOI URL |
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