羊边界病致病机制及宿主嗜性变化的研究进展

doi:10.16178/j.issn.0528-9017.20220460

浙江农业科学 ›› 2023, Vol. 64 ›› Issue (2): 474-479.DOI: 10.16178/j.issn.0528-9017.20220460

羊边界病致病机制及宿主嗜性变化的研究进展

赵泽阳^a^,^b(), 冯茜莉^a^,^b, 汪梦竹^a^,^b, 蒲飞洋^a^,^b, 马忠仁^a, 程燕^a^,^b^,^*()

a 生物医学研究中心, 西北民族大学, 甘肃兰州 730010
b 生命科学与工程学院, 西北民族大学, 甘肃兰州 730010

收稿日期:2022-08-28 出版日期:2023-02-11 发布日期:2023-02-16
通讯作者: 程燕
作者简介:程燕(1978—),女,宁夏银川人,高级实验师,博士,从事肿瘤与代谢疾病研究工作,E-mail:chengyan@xbmu.edu.cn。
赵泽阳(1997—),男,吉林长春人,硕士,从事病毒基因工程研究工作,E-mail:379233002@qq.com。
基金资助:
甘肃省科学技术厅自然基金(20JR5A505);中央高校基本科研业务费(31920200073)

Received:2022-08-28 Online:2023-02-11 Published:2023-02-16

摘要/Abstract

摘要：

羊边界病病毒(border disease virus,BDV)属于黄病毒科瘟病毒属,经常在牛、羊等反刍动物群体间广泛流行传播,能以多种动物为宿主且对健康动物具有一定危害。BDV感染反刍动物可引起持续性感染和免疫抑制,给畜牧业造成严重危害,且在多个国家和地区呈现出一定的流行性趋势。目前尚无公认的有效疫苗来预防BDV,所以如何科学饲养以及做好安全防控就成了重中之重。本文对BDV在牛群、羊群内的传播进行研究分析,有助于人们对BDV可能造成的风险进行预估并进行防控。因此,从BDV的分子生物学、流行现状、流行病学、临床症状以及与牛病毒性腹泻病毒(bovine viral diarrhea virus,BVDV)的混合感染来进行研究分析,有助于人们深入了解BDV致病及传播扩散的生物学机制,为该病的诊断、防治和疫苗研发提供新思路和策略。

关键词: 边界病病毒, 反刍动物, 持续感染, 流行病学, 宿主嗜性

中图分类号:

S858.26

赵泽阳, 冯茜莉, 汪梦竹, 蒲飞洋, 马忠仁, 程燕. 羊边界病致病机制及宿主嗜性变化的研究进展[J]. 浙江农业科学, 2023, 64(2): 474-479.

图/表 1

参考文献 32

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羊边界病致病机制及宿主嗜性变化的研究进展

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