Journal of Zhejiang Agricultural Sciences ›› 2025, Vol. 66 ›› Issue (1): 197-200.DOI: 10.16178/j.issn.0528-9017.20240564

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Application of the “detection and elimination method” in the purification of animal diseases in large-scale pig farms in Wenzhou

WU Bo1(), ZHANG Guoyong2, ZHAO Yan1, MA Wufei1, ZHOU Xuanlun1   

  1. 1. Wenzhou Animal Disease Prevention and Control Center, Wenzhou 325000, Zhejiang
    2. Animal Disease Prevention and Control Center in Cangnan County, Cangnan 325800, Zhejiang
  • Received:2024-07-16 Online:2025-01-11 Published:2025-01-14

Abstract:

In order to promote and improve the purification of animal diseases, this study takes the “detection and elimination method” as the core, and integrates purification technologies such as background investigation, immune program optimization, immune interference analysis, and biosafety system improvement. A large-scale pig farm in Wenzhou was taken as a demonstration site, with O-type aftosa virus and African swine fever virus as purification objects. After the purification was implemented, the production and epidemic prevention indicators of the pig farm had been improved. The qualified rate of aftosa virus immune antibodies had increased from 76.84% to 91.09%, the positive rate of aftosa virus wild-type antibodies had decreased from 4.21% to 0, the positive rate of aftosa virus wild-type nucleic acid had decreased from 3.68% to 0, and the positive rate of African swine fever virus wild-type nucleic acid had remained at zero. After four years of tracking and monitoring in the demonstration site, it has been promoted to more than 10 large-scale pig farms in the city. The overall qualified rate of O-type aftosa virus immune antibodies had shown an increasing trend year by year, while the number of positive antibodies and virus nucleic acid for aftosa virus had shown an overall decreasing trend year by year. The number of positive nucleic acid tested for African swine fever virus had been tracked and monitored over the years with a zero.

Key words: pig, detection elimination method, disease purification, aftosa virus, African swine fever virus

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