纳米材料在电化学检测亚硝酸盐的应用研究进展

doi:10.16178/j.issn.0528-9017.20230648

浙江农业科学 ›› 2024, Vol. 65 ›› Issue (6): 1468-1475.DOI: 10.16178/j.issn.0528-9017.20230648

纳米材料在电化学检测亚硝酸盐的应用研究进展

周环¹^,²^,³(), 郑晓杰¹^,²^,³, 邹盈¹^,²^,³^,^*(), 李彦坡¹^,²^,³, 叶剑¹^,²^,³, 胡超凡¹^,²^,³, 章志成⁴

1.温州市农业科学研究院食品科学研究所,浙江温州 325006
2.温州科技职业学院农业与生物技术学院,浙江温州 325006
3.温州市特色食品资源工程技术研究中心,浙江温州 325006
4.台州学院生命科学学院,浙江台州 318000

收稿日期:2023-06-14 出版日期:2024-06-11 发布日期:2024-06-20
通讯作者: 邹盈(1977—),女,宁波慈溪人,副教授,本科,研究方向为食品加工,E-mail: zouying@wzvcst.edu.com.cn。
作者简介:周环(1985—),男,浙江瑞安人,讲师,博士,研究方向为食品安全监测与控制,E-mail: zhouhuan@wzvcst.edu.cn。
基金资助:
浙江省教育厅一般科研项目(Y201840596);浙江省科技厅重点科技项目(2017C02039);温州市重大科技计划专项(2018ZN001)

Research progress on the application of nanomaterials in electrochemical detection of nitrite

ZHOU Huan¹^,²^,³(), ZHENG Xiaojie¹^,²^,³, ZOU Ying¹^,²^,³^,^*(), LI Yanpo¹^,²^,³, YE Jian¹^,²^,³, HU Chaofan¹^,²^,³, ZHANG Zhicheng⁴

1. Food Science Research Institute, Wenzhou Academy of Agricultural Sciences, Wenzhou 325006,Zhejiang
2. College of Agriculture and Biotechnology, Wenzhou Vocational College of Science and Technology, Wenzhou 325006, Zhejiang
3. Wenzhou Special Food Resource Engineering Technology Research Center, Wenzhou 325006,Zhejiang
4. School of Life Sciences, Taizhou University, Taizhou 318000,Zhejiang

Received:2023-06-14 Online:2024-06-11 Published:2024-06-20

摘要/Abstract

摘要：

亚硝酸盐作为一种常见的食品添加剂,能够稳定肉制品的色泽、提高风味、延长货架期。然而,亚硝酸盐同时又是一种有毒的污染物,长期过量摄入将会严重危害人体健康,因此,实现对其高灵敏度、高选择性的快速检测具有十分重要的意义。相较于其他传统检测方法,电化学检测法具有操作简单、选择性好、灵敏度高的优势。而电极材料作为电化学传感器的核心组成,其功能和界面性能都将影响到传感器的综合性能。文章详细介绍了碳、金属、金属氧化物、导电聚合物等纳米复合材料在亚硝酸盐电化学检测中的研究进展,重点详述了构建方法和检测结果,最后对亚硝酸盐传感器的未来发展趋势进行了讨论。

关键词: 亚硝酸盐, 电化学传感器, 电极材料, 研究进展

Abstract:

Nitrite, as a common food additive, can stabilize the color, enhance flavor, and extend shelf life of meat products. However, nitrite is also a toxic pollutant, and long-term excessive intake will seriously endanger human health. Therefore, achieving high sensitivity and selectivity for its rapid detection is of great significance. Compared with other traditional detection methods, electrochemical detection has the advantages of simple operation, good selectivity, and high sensitivity. As the core component of electrochemical sensors, electrode materials will have an impact on the overall performance of the sensor in terms of their functionality and interface performance. This article provides a detailed introduction to the research progress of nanocomposites such as carbon, metals, metal oxides, and conductive polymers in the electrochemical detection of nitrite. The construction methods and detection results are emphasized, and the future development trends of nitrite sensors are discussed.

Key words: nitrite, electrochemical sensor, electrode material, research progress

中图分类号:

TS207.3

周环, 郑晓杰, 邹盈, 李彦坡, 叶剑, 胡超凡, 章志成. 纳米材料在电化学检测亚硝酸盐的应用研究进展[J]. 浙江农业科学, 2024, 65(6): 1468-1475.

ZHOU Huan, ZHENG Xiaojie, ZOU Ying, LI Yanpo, YE Jian, HU Chaofan, ZHANG Zhicheng. Research progress on the application of nanomaterials in electrochemical detection of nitrite[J]. Journal of Zhejiang Agricultural Sciences, 2024, 65(6): 1468-1475.

图/表 5

图1 电化学检测亚硝酸盐的原理图

Fig.1 Schematic diagram of electrochemical detection of nitrite

图2 NrGO修饰玻碳电极制备示意图[15] 和N-CNFs@N-GRQDs亚硝酸盐伏安传感器制备过程[17] A表示NrGO修饰玻碳电极制备示意图,B表示N-CNFs@N-GRQDs亚硝酸盐伏安传感器制备过程。

Fig.2 Schematic diagram of NrGO modified glassy carbon electrode preparation[15] and N-CNFs@N-GRQDs Preparation process of nitrite voltammetric sensor[17]

图3 金属材料示意图 A表示Cu/MWCNTs/GC电极的制备示意图[25];B表示用于亚硝酸盐传感的Au NPs/MoS2/GCE复合物的合成示意图[26]; C表示ERGO/AuNPs的制备和用于电催化亚硝酸盐氧化的示意图[27];D表示Au-PtNPs/PyTS NG/GCE电极的制备过程示意图[30]。

Fig.3 Schematic diagram of metal materials

表1 不同金属复合材料修饰电极在实际样品中测定亚硝酸盐的结果比较

Table 1 Comparison of results for determining nitrite in actual samples with different metal composite material modified electrodes

电极材料	线性范围/(μmol·L^-1)	检出限	检测样品	参考文献
ERGO/AuNPs/SPCE	1~6 000	0.13 μmol·L^-1	矿泉水、虾干、腌/咸鱼和香肠	[27]
Ag-rGO	0.1~120	12 nmol·L^-1	池塘水	[28]
f-MWCNT/PdNPs	0.05~2 887.6	22 nmol·L^-1	自来水、池塘水、饮用水	[29]
Au-Pt NPs/PyTS-NG	0.5~1 621	0.19 mmol·L^-1	火腿肠和自来水	[30]
MWCNTs@Au-Pd/GR	0.02~55.0	9.44 nmol·L^-1	香肠、奶酪、植物食品、土壤、矿泉水、自来水	[32]
Ag/Cu/MWNTs	1.0~1.0×10³	0.02 μmol·L^-1	湖水、饮用水、海水	[33]
Au-Pd/rGO	0.05~1.0×10³	0.02 μmol·L^-1	自来水	[34]
CoNi/GR	0.1~30、30~330	0.05 mmol·L^-1	矿泉水、香肠、干酪	[35]

图4 金属氧化物材料示意图 A表示α-Fe2O3-NAs/CF复合材料合成路线示意图[40];B表示MoO3/Co3O4/GC制备示意图[42];C表示用于亚硝酸盐检测的三元CuO/H-C3N4/rGO修饰玻碳电极传感器的合成示意图[43]。

Fig.4 Schematic diagram of metal oxide materials

参考文献 48

[1]	ZHAO K, SONG H Y, ZHUANG S Q, et al. Determination of nitrite with the electrocatalytic property to the oxidation of nitrite on thionine modified aligned carbon nanotubes[J]. Electrochemistry Communications, 2007, 9(1): 65-70.
[2]	NAKAMURA K, YOSHIDA Y, MIKAMI I, et al. Selective hydrogenation of nitrate in water over Cu-Pd/mordenite[J]. Applied Catalysis B: Environmental, 2006, 65(1/2): 31-36.
[3]	JAKSZYN P, GONZALEZ C A. Nitrosamine and related food intake and gastric and oesophageal cancer risk: a systematic review of the epidemiological evidence[J]. World Journal of Gastroenterology, 2006, 12(27): 4296-4303.
[4]	SALIMI A, KURD M, TEYMOURIAN H, et al. Highly sensitive electrocatalytic detection of nitrite based on SiC nanoparticles/amine terminated ionic liquid modified glassy carbon electrode integrated with flow injection analysis[J]. Sensors and Actuators B: Chemical, 2014, 205: 136-142.
[5]	HILSHEIMER R, HARWIG J. Colorimetric determination of nitrite from meat and other foods: an alternative colour reagent for the carcinogenic 1-naphthylamine and an improved extraction method[J]. Canadian Institute of Food Science and Technology Journal, 1976, 9(4): 225-227.
[6]	GARCÍA-ROBLEDO E, CORZO A, PAPASPYROU S. A fast and direct spectrophotometric method for the sequential determination of nitrate and nitrite at low concentrations in small volumes[J]. Marine Chemistry, 2014, 162:30-36.
[7]	SALHI E, VON GUNTEN U. Simultaneous determination of bromide, bromate and nitrite in low μg·l^-1 levels by ion chromatography without sample pretreatment[J]. Water Research, 1999, 33(15): 3239-3244.
[8]	JEDLIČKOVÁ V, PALUCH Z, ALUŠÍK Š. Determination of nitrate and nitrite by high-performance liquid chromatography in human plasma[J]. Journal of Chromatography B, 2002, 780(1): 193-197.
[9]	SMYTHE G A, MATANOVIC G. Specific analysis of nitrate and nitrite by gas chromatography/mass spectrometry[J]. Methods in Enzymology, 2002, 359:148-157.
[10]	NOROOZIFAR M, KHORASANI-MOTLAGH M, TAHERI A, et al. Application of manganese(Ⅳ) dioxide microcolumn for determination and speciation of nitrite and nitrate using a flow injection analysis-flame atomic absorption spectrometry system[J]. Talanta, 2007, 71(1): 359-364.
[11]	KOZUB B R, REES N V, COMPTON R G. Electrochemical determination of nitrite at a bare glassy carbon electrode; why chemically modify electrodes?[J]. Sensors and Actuators B: Chemical, 2010, 143(2): 539-546.
[12]	YANG M, YAN Y J, SHI H X, et al. A novel fluorescent sensors for sensitive detection of nitrite ions[J]. Materials Chemistry and Physics, 2020, 239:122121.
[13]	ZHENG P, KASANI S, SHI X F, et al. Detection of nitrite with a surface-enhanced Raman scattering sensor based on silver nanopyramid array[J]. Analytica Chimica Acta, 2018, 1040: 158-165.
[14]	LI S F, QU J Y, WANG Y, et al. A novel electrochemical sensor based on carbon nanoparticle composite films for the determination of nitrite and hydrogen peroxide[J]. Analytical Methods, 2016, 8(21): 4204-4210.
[15]	CHEN D, JIANG J J, DU X Z. Electrocatalytic oxidation of nitrite using metal-free nitrogen-doped reduced graphene oxide nanosheets for sensitive detection[J]. Talanta, 2016, 155:329-335.
[16]	MEHMETI E, STANKOVIĆ D M, HAJRIZI A, et al. The use of graphene nanoribbons as efficient electrochemical sensing material for nitrite determination[J]. Talanta, 2016, 159: 34-39.
[17]	LI L B, LIU D, WANG K, et al. Quantitative detection of nitrite with N-doped graphene quantum dots decorated N-doped carbon nanofibers composite-based electrochemical sensor[J]. Sensors and Actuators B: Chemical, 2017, 252: 17-23.
[18]	DING B J, WANG H, TAO S Y, et al. Preparing electrochemical active hierarchically porous carbons for detecting nitrite in drinkable water[J]. RSC Advances, 2016, 6(9): 7302-7309.
[19]	ZHOU S H, WU H M, WU Y, et al. Hemi-ordered nanoporous carbon electrode material for highly selective determination of nitrite in physiological and environmental systems[J]. Thin Solid Films, 2014, 564:406-411.
[20]	MIAO P, SHEN M, NING L M, et al. Functionalization of platinum nanoparticles for electrochemical detection of nitrite[J]. Analytical and Bioanalytical Chemistry, 2011, 399(7): 2407-2411.
[21]	MANIKANDAN V S, LIU Z G, CHEN A C. Simultaneous detection of hydrazine, sulfite, and nitrite based on a nanoporous gold microelectrode[J]. Journal of Electroanalytical Chemistry, 2018, 819: 524-532.
[22]	GUPTA S, PRAKASH R. Photochemical assisted formation of silver nano dendrites and their application in amperometric sensing of nitrite[J]. RSC Advances, 2014, 4(15): 7521-7527.
[23]	CHEN S S, SHI Y C, WANG A J, et al. Free-standing Pt nanowire networks with clean surfaces: highly sensitive electrochemical detection of nitrite[J]. Journal of Electroanalytical Chemistry, 2017, 791: 131-137.
[24]	YANG J H, YANG H T, LIU S H, et al. Microwave-assisted synthesis graphite-supported Pd nanoparticles for detection of nitrite[J]. Sensors and Actuators B: Chemical, 2015, 220: 652-658.
[25]	MANOJ D, SARAVANAN R, SANTHANALAKSHMI J, et al. Towards green synthesis of monodisperse Cu nanoparticles: an efficient and high sensitive electrochemical nitrite sensor[J]. Sensors and Actuators B: Chemical, 2018, 266: 873-882.
[26]	ZHANG S, TANG Y P, CHEN Y Y, et al. Synthesis of gold nanoparticles coated on flower-like MoS₂ microsphere and their application for electrochemical nitrite sensing[J]. Journal of Electroanalytical Chemistry, 2019, 839: 195-201.
[27]	JIAN J M, FU L F, JI J Y, et al. Electrochemically reduced graphene oxide/gold nanoparticles composite modified screen-printed carbon electrode for effective electrocatalytic analysis of nitrite in foods[J]. Sensors and Actuators B: Chemical, 2018, 262:125-136.
[28]	AHMAD R, MAHMOUDI T, AHN M S, et al. Fabrication of sensitive non-enzymatic nitrite sensor using silver-reduced graphene oxide nanocomposite[J]. Journal of Colloid and Interface Science, 2018, 516: 67-75.
[29]	THIRUMALRAJ B, PALANISAMY S, CHEN S M, et al. Amperometric detection of nitrite in water samples by use of electrodes consisting of palladium-nanoparticle-functionalized multi-walled carbon nanotubes[J]. Journal of Colloid and Interface Science, 2016, 478: 413-420.
[30]	LI Z, AN Z Z, GUO Y Y, et al. Au-Pt bimetallic nanoparticles supported on functionalized nitrogen-doped graphene for sensitive detection of nitrite[J]. Talanta, 2016, 161: 713-720.
[31]	YANG Y, ZHANG J, LI Y W, et al. Ni nanosheets evenly distributed on MoS₂ for selective electrochemical detection of nitrite[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, 625: 126865.
[32]	REZAEI M. An Au-Pd@MWCNT/graphene modified carbon paste electrode as a novel nano-composite sensor for the trace determination of nitrite[J]. Analytical and Bioanalytical Electrochemistry, 2016, 8(3): 287-303.
[33]	ZHANG Y, NIE J T, WEI H Y, et al. Electrochemical detection of nitrite ions using Ag/Cu/MWNT nanoclusters electrodeposited on a glassy carbon electrode[J]. Sensors and Actuators B: Chemical, 2018, 258: 1107-1116.
[34]	LI S S, HU Y Y, WANG A J, et al. Simple synthesis of worm-like Au-Pd nanostructures supported on reduced graphene oxide for highly sensitive detection of nitrite[J]. Sensors and Actuators B: Chemical, 2015, 208: 468-474.
[35]	GHOLIVAND M B, JALALVAND A R, GOICOECHEA H C. Computer-assisted electrochemical fabrication of a highly selective and sensitive amperometric nitrite sensor based on surface decoration of electrochemically reduced graphene oxide nanosheets with CoNi bimetallic alloy nanoparticles[J]. Materials Science and Engineering: C, 2014, 40: 109-120.
[36]	LI D, KANER R B. Shape and aggregation control of nanoparticles: not Shaken, not stirred[J]. Journal of the American Chemical Society, 2006, 128(3): 968-975.
[37]	MARCANO D C, KOSYNKIN D V, BERLIN J M, et al. Improved synthesis of graphene oxide[J]. ACS Nano, 2010, 4(8): 4806-4814.
[38]	KASSAEE M Z, MOTAMEDI E, MAJDI M. Magnetic Fe₃O₄-graphene oxide/polystyrene: fabrication and characterization of a promising nanocomposite[J]. Chemical Engineering Journal, 2011, 172(1): 540-549.
[39]	SUDHA V, MOHANTY S A, THANGAMUTHU R. Facile e synthesis of Co₃O₄ disordered circular sheets for selective electrochemical determination of nitrite[J]. New Journal of Chemistry, 2018, 42(14): 11869-11877.
[40]	MA Y, SONG X Y, GE X, et al. In situ growth of α-Fe₂O₃ nanorod arrays on 3D carbon foam as an efficient binder-free electrode for highly sensitive and specific determination of nitrite[J]. Journal of Materials Chemistry A, 2017, 5(9): 4726-4736.
[41]	WANG R, WANG Z, XIANG X J, et al. MnO₂ nanoarrays: an efficient catalyst electrode for nitrite electroreduction toward sensing and NH₃ synthesis applications[J]. Chemical Communications, 2018, 54(73): 10340-10342.
[42]	ZHE T T, LI M Y, LI F, et al. Integrating electrochemical sensor based on MoO₃/Co₃O₄ heterostructure for highly sensitive sensing of nitrite in sausages and water[J]. Food Chemistry, 2022, 367: 130666.
[43]	LI Y, CHENG C, YANG Y P, et al. A novel electrochemical sensor based on CuO/H-C₃N₄/rGO nanocomposite for efficient electrochemical sensing nitrite[J]. Journal of Alloys and Compounds, 2019, 798: 764-772.
[44]	COSNIER S, HOLZINGER M. Electrosynthesized polymers for biosensing[J]. Chemical Society Reviews, 2011, 40(5): 2146-2156.
[45]	CHENG Y H, KUNG C W, CHOU L Y, et al. Poly(3,4-ethylenedioxythiophene) (PEDOT) hollow microflowers and their application for nitrite sensing[J]. Sensors and Actuators B: Chemical, 2014, 192: 762-768.
[46]	XU F G, LIU Y, DING G H, et al. Three dimensional macroporous poly(3,4-ethylenedioxythiophene) structure: Electrodeposited preparation and sensor application[J]. Electrochimica Acta, 2014, 150: 223-231.
[47]	TIAN F Y, LI H J, LI M J, et al. Synthesis of one-dimensional poly(3,4-ethylenedioxythiophene)-graphene composites for the simultaneous detection of hydroquinone,catechol, resorcinol, and nitrite[J]. Synthetic Metals, 2017, 226: 148-156.
[48]	SUMA B P, ADARAKATTI P S, KEMPAHANUMAKKAGARI S K, et al. A new polyoxometalate/rGO/Pani composite modified electrode for electrochemical sensing of nitrite and its application to food and environmental samples[J]. Materials Chemistry and Physics, 2019, 229: 269-278.

纳米材料在电化学检测亚硝酸盐的应用研究进展

Research progress on the application of nanomaterials in electrochemical detection of nitrite

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